Developing new cancer therapies and improving the quality of patients’ lives is at the heart of everything we do. Our goal is to create effective new therapies that provide meaningful benefit to patients with cancer.
Actively Recruiting Patients
Clinical trials are an essential part of discovering new cancer therapies and making them available to those in need. We are actively seeking patient volunteers for the following clinical trials:

Clinical Trial
Ompenaclid (RGX-202)
This study is designed to evaluate ompenaclid (RGX-202) in combination with standard-of-care therapy. Patients diagnosed with advanced colorectal cancer may be able to participate in our clinical trial.
Clinical Trial
Abequolixron (RGX-104)
This study is designed to evaluate RGX-104 in combination with other agents, including standard-of-care therapy. Patients diagnosed with advanced NSCLC or Endometrial Cancer may be able to participate in our clinical trial.
About Ompenaclid (RGX-202)
About Abequolixron (RGX-104)
Ompenaclid (RGX-202) is an oral small molecule inhibitor of SLC6A8 that induces apoptosis (cell death) of colorectal cancer cells
RGX-104 is an oral small molecule activator of LXR/APOE that inhibits the growth of tumor blood vessels (angiogenesis) and activates tumor myeloid cells to enhance the immune response against tumors.